Details of Superfamily a.4.5

Diagram of relationships between the families present in a.4.5 Superfamily.

Click on the figure for a larger image.


SCOP class : All alpha proteins

SCOP fold : DNA/RNA-binding 3-helical bundle

SCOP superfamily : "Winged helix" DNA-binding domain

Pfam families present in this Superfamily

AphA_like -- Putative AphA-like transcriptional regulator (PF14557)

Arg_repressor -- Arginine repressor, DNA binding domain (PF01316)

ArsR -- ArsR transcriptional regulator (PF09824)

B-block_TFIIIC -- B-block binding subunit of TFIIIC (PF04182)

CDT1 -- DNA replication factor CDT1 like (PF08839)

Cdc6_C -- CDC6, C terminal (PF09079)

Crp -- Bacterial regulatory proteins, crp family (PF00325)

Cullin_Nedd8 -- Cullin protein neddylation domain (PF10557)

DEP -- Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) (PF00610)

DUF1495 -- Winged helix DNA-binding domain (DUF1495) (PF07381)

DUF2250 -- Uncharacterized protein conserved in archaea (DUF2250) (PF10007)

DUF2513 -- Hypothetical protein (DUF2513) (PF10711)

DUF2551 -- Protein of unknown function (DUF2551) (PF10826)

DUF3116 -- Protein of unknown function (DUF3116) (PF11313)

DUF387 -- Putative transcriptional regulators (Ypuh-like) (PF04079)

DUF4364 -- Domain of unknown function (DUF4364) (PF14277)

DUF4423 -- Domain of unknown function (DUF4423) (PF14394)

DUF480 -- Protein of unknown function, DUF480 (PF04337)

Dimerisation -- Dimerisation domain (PF08100)

DsrD -- Dissimilatory sulfite reductase D (DsrD) (PF08679)

E2F_TDP -- E2F/DP family winged-helix DNA-binding domain (PF02319)

Ets -- Ets-domain (PF00178)

FUR -- Ferric uptake regulator family (PF01475)

FaeA -- FaeA-like protein (PF04703)

Fe_dep_repress -- Iron dependent repressor, N-terminal DNA binding domain (PF01325)

FeoC -- FeoC like transcriptional regulator (PF09012)

Fork_head -- Fork head domain (PF00250)

Ftsk_gamma -- Ftsk gamma domain (PF09397)

GntR -- Bacterial regulatory proteins, gntR family (PF00392)

HSF_DNA-bind -- HSF-type DNA-binding (PF00447)

HTH_1 -- Bacterial regulatory helix-turn-helix protein, lysR family (PF00126)

HTH_10 -- HTH DNA binding domain (PF04967)

HTH_11 -- HTH domain (PF08279)

HTH_12 -- Ribonuclease R winged-helix domain (PF08461)

HTH_20 -- Helix-turn-helix domain (PF12840)

HTH_24 -- Winged helix-turn-helix DNA-binding (PF13412)

HTH_27 -- Winged helix DNA-binding domain (PF13463)

HTH_34 -- Winged helix DNA-binding domain (PF13601)

HTH_36 -- Helix-turn-helix domain (PF13730)

HTH_39 -- Helix-turn-helix domain (PF14090)

HTH_41 -- Helix-turn-helix domain (PF14502)

HTH_45 -- Winged helix-turn-helix (PF14947)

HTH_5 -- Bacterial regulatory protein, arsR family (PF01022)

HTH_9 -- RNA polymerase III subunit RPC82 helix-turn-helix domain (PF08221)

HTH_AsnC-type -- AsnC-type helix-turn-helix domain (PF13404)

HTH_CodY -- CodY helix-turn-helix domain (PF08222)

HTH_Crp_2 -- Crp-like helix-turn-helix domain (PF13545)

HTH_DeoR -- DeoR-like helix-turn-helix domain (PF08220)

HTH_IclR -- IclR helix-turn-helix domain (PF09339)

HTH_Mga -- M protein trans-acting positive regulator (MGA) HTH domain (PF08280)

HTH_Tnp_Tc3_2 -- Transposase (PF01498)

HemN_C -- HemN C-terminal domain (PF06969)

HrcA_DNA-bdg -- Winged helix-turn-helix transcription repressor, HrcA DNA-binding (PF03444)

HxlR -- HxlR-like helix-turn-helix (PF01638)

IBD -- Transcription-initiator DNA-binding domain IBD (PF10416)

IRF -- Interferon regulatory factor transcription factor (PF00605)

KicB -- KicB killing factor (PF03882)

La -- La domain (PF05383)

LexA_DNA_bind -- LexA DNA binding domain (PF01726)

Linker_histone -- linker histone H1 and H5 family (PF00538)

MarR -- MarR family (PF01047)

MarR_2 -- MarR family (PF12802)

MotA_activ -- Transcription factor MotA, activation domain (PF09114)

Mrr_N -- Mrr N-terminal domain (PF14338)

PCI_Csn8 -- COP9 signalosome, subunit CSN8 (PF10075)

PaaX -- PaaX-like protein (PF07848)

PadR -- Transcriptional regulator PadR-like family (PF03551)

Penicillinase_R -- Penicillinase repressor (PF03965)

Phage_rep_org_N -- N-terminal phage replisome organiser (Phage_rep_org_N) (PF09681)

Pox_D5 -- Poxvirus D5 protein-like (PF03288)

PuR_N -- Bacterial purine repressor, N-terminal (PF09182)

Put_DNA-bind_N -- Putative DNA-binding protein N-terminus (PF06971)

RP-C -- Replication protein C N-terminal domain (PF03428)

RQC -- RQC domain (PF09382)

RTP -- Replication terminator protein (PF02334)

Rad21_Rec8 -- Conserved region of Rad21 / Rec8 like protein (PF04824)

RepL -- Firmicute plasmid replication protein (RepL) (PF05732)

Ribosomal_S19e -- Ribosomal protein S19e (PF01090)

Rio2_N -- Rio2, N-terminal (PF09202)

Rrf2 -- Transcriptional regulator (PF02082)

RuvB_C -- Holliday junction DNA helicase ruvB C-terminus (PF05491)

S10_plectin -- Plectin/S10 domain (PF03501)

STN1_2 -- CST, Suppressor of cdc thirteen homolog, complex subunit STN1 (PF09170)

SelB-wing_3 -- Elongation factor SelB, winged helix (PF09107)

SgrR_N -- Sugar transport-related sRNA regulator N-term (PF12793)

Sulfolobus_pRN -- Sulfolobus plasmid regulatory protein (PF05584)

TFIIE_alpha -- TFIIE alpha subunit (PF02002)

TFIIE_beta -- TFIIE beta subunit core domain (PF02186)

TFIIF_alpha -- Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) (PF05793)

Tn7_Tnp_TnsA_C -- TnsA endonuclease C terminal (PF08721)

TrmB -- Sugar-specific transcriptional regulator TrmB (PF01978)

YjcQ -- YjcQ protein (PF09639)

z-alpha -- Adenosine deaminase z-alpha domain (PF02295)