The potential new superfamilies are Pfam families that have been related to each other without the use of structural information. The PNSFs could provide a very important resource for structural genomics initiative targets.


PNSF no. 1


- NADH dehydrogenase (PF00146)
- Sodium:neurotransmitter symporter family (PF00209)
- Sec-independent protein translocase protein (TatC) (PF00902)
- Glycosyl transferase family 4 (PF00953)
- HCO3- transporter family (PF00955)
- Sodium/hydrogen exchanger family (PF00999)
- Inhibitor of apoptosis-promoting Bax1 (PF01027)
- Formate/nitrite transporter (PF01226)
- Sodium:alanine symporter family (PF01235)
- Domain of unknown function DUF20 (PF01594)
- Acyltransferase family (PF01757)
- LysE type translocator (PF01810)
- Membrane protein of unknown function DUF63 (PF01889)
- Cobalt uptake substrate-specific transmembrane region (PF01891)
- MarC family integral membrane protein (PF01914)
- Sulfite exporter TauE/SafE (PF01925)
- Integral membrane protein DUF92 (PF01940)
- Polysaccharide biosynthesis protein (PF01943)
- Fungal pheromone mating factor STE2 GPCR (PF02116)
- AmiS/UreI family transporter (PF02293)
- Cytochrome oxidase subunit II (PF02322)
- Dolichyl-phosphate-mannose-protein mannosyltransferase (PF02366)
- Cation transport protein (PF02386)
- GntP family permease (PF02447)
- Carbon starvation protein CstA (PF02554)
- Cytochrome oxidase assembly protein (PF02628)
- Glycerol-3-phosphate acyltransferase (PF02660)
- Bacitracin resistance protein BacA (PF02673)
- Colicin V production protein (PF02674)
- FtsX-like permease family (PF02687)
- Domain of unknown function DUF221 (PF02714)
- Haemolysin-III related (PF03006)
- NQR2, RnfD, RnfE family (PF03116)
- EXS family (PF03124)
- ALG6, ALG8 glycosyltransferase family (PF03155)
- Eukaryotic cytochrome b561 (PF03188)
- Otopetrin (PF03189)
- Tryptophan/tyrosine permease family (PF03222)
- Urea transporter (PF03253)
- Caenorhabditis protein of unknown function, DUF267 (PF03268)
- Serine incorporator (Serinc) (PF03348)
- CcmB protein (PF03379)
- 2-hydroxycarboxylate transporter family (PF03390)
- Membrane transport protein (PF03547)
- Benzoate membrane transport protein (PF03594)
- Cadmium resistance transporter (PF03596)
- Conserved hypothetical protein 698 (PF03601)
- Anaerobic c4-dicarboxylate membrane transporter (PF03605)
- PTS system sorbose-specific iic component (PF03609)
- Virulence factor BrkB (PF03631)
- Predicted permease YjgP/YjgQ family (PF03739)
- Integral membrane protein TerC family (PF03741)
- AbgT putative transporter family (PF03806)
- 2-keto-3-deoxygluconate permease (PF03812)
- Potassium-transporting ATPase A subunit (PF03814)
- High-affinity nickel-transport protein (PF03824)
- Spore germination protein (PF03845)
- Alg9-like mannosyltransferase family (PF03901)
- Na+-transporting oxaloacetate decarboxylase beta subunit (PF03977)
- Domain of unknown function (DUF368) (PF04018)
- rod shape-determining protein MreD (PF04093)
- Protein of unknown function (DUF401) (PF04165)
- Signal peptide peptidase (PF04258)
- Protein of unknown function (DUF456) (PF04306)
- Protein of unknown function (DUF475) (PF04332)
- Ethanolamine utilisation protein, EutH (PF04346)
- Plasma-membrane choline transporter (PF04515)
- TrbL/VirB6 plasmid conjugal transfer protein (PF04610)
- FAR-17a/AIG1-like protein (PF04750)
- LMBR1-like membrane protein (PF04791)
- DIE2/ALG10 family (PF04922)
- DMSO reductase anchor subunit (DmsC) (PF04976)
- Mannosyltransferase (PIG-M) (PF05007)
- Putative ammonia monooxygenase (PF05145)
- ALG3 protein (PF05208)
- UNC-50 family (PF05216)
- Branched-chain amino acid transport protein (PF05525)
- Protein of unknown function (DUF819) (PF05684)
- TraX protein (PF05857)
- Bacterial ABC transporter protein EcsB (PF05975)
- Bacterial protein of unknown function (DUF898) (PF05987)
- Eukaryotic protein of unknown function (DUF914) (PF06027)
- Protein of unknown function (DUF975) (PF06161)
- Protein of unknown function (DUF979) (PF06166)
- Protein of unknown function (DUF981) (PF06168)
- QueT transporter (PF06177)
- ABC-2 family transporter protein (PF06182)
- Protein of unknown function (DUF996) (PF06195)
- L-rhamnose-proton symport protein (RhaT) (PF06379)
- Bacterial Na+/H+ antiporter B (NhaB) (PF06450)
- Protein of unknown function (DUF1084) (PF06454)
- Protein of unknown function (DUF1119) (PF06550)
- SUR7/PalI family (PF06687)
- Protein of unknown function (DUF1189) (PF06691)
- Uncharacterised protein family (UPF0259) (PF06790)
- Sugar transport protein (PF06800)
- Lung seven transmembrane receptor (PF06814)
- WzyE protein (PF06899)
- Protein of unknown function (DUF1275) (PF06912)
- Protein of unknown function (DUF1282) (PF06930)
- Na+/H+ antiporter 1 (PF06965)
- ECF-type riboflavin transporter, S component (PF07155)
- Progressive ankylosis protein (ANKH) (PF07260)
- Etoposide-induced protein 2.4 (EI24) (PF07264)
- Protein of unknown function (DUF1504) (PF07399)
- Heptaprenyl diphosphate synthase component I (PF07456)
- 5TMR of 5TMR-LYT (PF07694)
- 7TM diverse intracellular signalling (PF07695)
- 7TM receptor with intracellular HD hydrolase (PF07698)
- 10 TM Acyl Transferase domain found in Cas1p (PF07779)
- Protein of unknown function (DUF1646) (PF07854)
- CEO family (DUF1632) (PF07857)
- YibE/F-like protein (PF07907)
- 7tm Chemosensory receptor (PF08395)
- ICE2 (PF08426)
- UAA transporter family (PF08449)
- PalH/RIM21 (PF08733)
- Probable cobalt transporter subunit (CbtA) (PF09490)
- Thiamine-precursor transporter protein (ThiW) (PF09512)
- Thiamine transporter protein (Thia_YuaJ) (PF09515)
- Integral membrane protein (intg_mem_TP0381) (PF09529)
- Stage III sporulation protein AE (spore_III_AE) (PF09546)
- Protein of unknown function (DUF2029) (PF09594)
- Hypothetical bacterial integral membrane protein (Trep_Strep) (PF09605)
- Putative integral membrane protein (DUF2391) (PF09622)
- Transmembrane exosortase (Exosortase_EpsH) (PF09721)
- Tumour-associated protein (PF09746)
- XK-related protein (PF09815)
- Predicted membrane protein (DUF2079) (PF09852)
- Predicted transporter (DUF2162) (PF09930)
- Predicted membrane protein (DUF2232) (PF09991)
- Predicted transmembrane protein 161AB (PF10268)
- Frag1/DRAM/Sfk1 family (PF10277)
- Protein of unknown function (PF10797)
- Protein of unknown function (DUF2776) (PF10951)
- Protein of unknown function (DUF3169) (PF11368)
- Protein of unknown function (DUF2899) (PF11449)
- Protein of unknown function (DUF3360) (PF11840)
- Protein of unknown function (DUF3533) (PF12051)
- Protein of unknown function (DUF3537) (PF12056)
- Protein of unknown function (DUF3623) (PF12291)
- Ca2+ regulator and membrane fusion protein Fig1 (PF12351)
- ABC-2 family transporter protein (PF12679)
- ABC-2 family transporter protein (PF12698)
- Mechanosensitive ion channel inner membrane domain 1 (PF12794)
- Protein of unknown function (DUF3902) (PF13042)
- Domain of unknown function (DUF4010) (PF13194)
- Protein of unknown function (DUF4013) (PF13197)
- Protein of unknown function (DUF4079) (PF13301)
- Phosphotransferase system, EIIC (PF13303)
- Domain of unknown function (DUF4084) (PF13321)
- ABC-2 family transporter protein (PF13346)
- Cytochrome C biogenesis protein transmembrane region (PF13386)
- Polysaccharide biosynthesis protein (PF13440)
- Domain of unknown function (DUF4117) (PF13491)
- SBF-like CPA transporter family (DUF4137) (PF13593)
- Domain of unknown function (DUF4153) (PF13687)
- Protein of unknown function (DUF4199) (PF13858)
- Domain of unknown function (DUF4203) (PF13886)
- Domain of unknown function (DUF4271) (PF14093)
- Domain of unknown function (DUF4386) (PF14329)
- TMEM164 family (PF14808)
- Beta-carotene 15,15'-dioxygenase (PF15461)


PNSF no. 2


- Osteopontin (PF00865)
- Vinculin family (PF01044)
- Granin (chromogranin or secretogranin) (PF01271)
- Transferrin binding protein-like solute binding protein (PF01298)
- Myosin tail (PF01576)
- MARCKS family (PF02063)
- Progesterone receptor (PF02161)
- Transcription factor IIA, alpha/beta subunit (PF03153)
- Atrophin-1 family (PF03154)
- High molecular weight glutenin subunit (PF03157)
- SART-1 family (PF03343)
- Daxx Family (PF03344)
- Treacher Collins syndrome protein Treacle (PF03546)
- Actin interacting protein 3 (PF03915)
- Paf1 (PF03985)
- Microtubule associated protein (MAP65/ASE1 family) (PF03999)
- Mpp10 protein (PF04006)
- Spc97 / Spc98 family (PF04130)
- Single-stranded DNA binding protein, SSDP (PF04503)
- Utp14 protein (PF04615)
- PEA3 subfamily ETS-domain transcription factor N terminal domain (PF04621)
- Rab effector MyRIP/melanophilin C-terminus (PF04698)
- Agrobacterium VirD5 protein (PF04730)
- Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) (PF05091)
- Protein of unknown function (DUF688) (PF05097)
- SDA1 (PF05285)
- Protein of unknown function (DUF740) (PF05340)
- Brain acid soluble protein 1 (BASP1 protein) (PF05466)
- Prominin (PF05478)
- Mitotic checkpoint protein (PF05557)
- Protein of unknown function (DUF810) (PF05664)
- Weak chloroplast movement under blue light (PF05701)
- Ycf1 (PF05758)
- Bacterial protein of unknown function (DUF839) (PF05787)
- Plant protein of unknown function (DUF869) (PF05911)
- RIB43A (PF05914)
- APC basic domain (PF05956)
- Septation ring formation regulator, EzrA (PF06160)
- Centromere/kinetochore Zw10 (PF06248)
- Plant specific eukaryotic initiation factor 4B (PF06273)
- Kinesin-related (PF06548)
- SGT1 protein (PF07093)
- Alpha helical coiled-coil rod protein (HCR) (PF07111)
- Protein of unknown function (DUF1421) (PF07223)
- Dentin matrix protein 1 (DMP1) (PF07263)
- Protein of unknown function (DUF1509) (PF07420)
- Nop53 (60S ribosomal biogenesis) (PF07767)
- Rec10 / Red1 (PF07964)
- Fibrinogen binding protein (PF08017)
- MAP2/Tau projection domain (PF08377)
- Dynein heavy chain, N-terminal region 1 (PF08385)
- Fungal Nap binding protein NBP1 (PF08537)
- Nucleoporin Nup153-like (PF08604)
- Alkali metal cation/H+ antiporter Nha1 C terminus (PF08619)
- DNA replication regulator SLD3 (PF08639)
- BUD22 (PF09073)
- Frequency clock protein (PF09421)
- WTX protein (PF09422)
- Nuclear protein Es2 (PF09751)
- Exocyst complex component Sec3 (PF09763)
- Golgin subfamily A member 5 (PF09787)
- DNA damage checkpoint protein (PF09798)
- RIM-binding protein of the cytomatrix active zone (PF10174)
- Microtubule-binding protein MIP-T3 (PF10243)
- TORC1 subunit TCO89 (PF10452)
- Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E (PF10477)
- N-methyl D-aspartate receptor 2B3 C-terminus (PF10565)
- Protein of unknown function (DUF2967) (PF11179)
- Protein of unknown function (DUF3160) (PF11369)
- Protein of unknown function (DUF3210) (PF11489)
- Protein of unknown function (DUF3466) (PF11949)
- Domain of unknown function (DUF3498) (PF12004)
- Duffy-antigen binding protein (PF12361)
- Protein of unknown function (DUF3676) (PF12429)
- Domain of unknown function (DUF3827) (PF12877)
- AAA domain (PF13166)
- Domain of unknown function (DUF4175) (PF13779)
- HAUS augmin-like complex subunit 5 (PF14817)
- Domain of unknown function (PF14925)
- Domain of unknown function (DUF4584) (PF15223)
- Coiled-coil domain-containing protein 14 (PF15254)
- Dapper (PF15268)
- NHS-like (PF15273)
- Nuclear fragile X mental retardation-interacting protein 2 (PF15293)
- A-kinase anchor protein 2 C-terminus (PF15304)
- CEP170 C-terminus (PF15308)
- Ewing's tumour-associated antigen 1 homologue (PF15350)
- Susceptibility to monomelic amyotrophy (PF15352)
- Enamelin (PF15362)
- Uncharacterised protein KIAA1328 (PF15369)
- Specifically androgen-regulated gene protein (PF15385)
- Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter (PF15439)
- THRAP3/BCLAF1 family (PF15440)
- Nephrin and CD2AP-binding protein, Dendrin (PF15498)
- Nuclear protein MDM1 (PF15501)
- Domain of unknown function (DUF4650) (PF15509)
- Centromere kinetochore component CENP-T (PF15511)
- FSIP1 family (PF15554)
- Domain of unknown function (DUF4659) (PF15558)
- Cancer/testis gene family 47 (PF15623)


PNSF no. 3


- Astrovirus capsid protein precursor (PF03115)
- Ribophorin I (PF04597)
- Cytomegalovirus UL84 protein (PF06284)
- Clostridium P-47 protein (PF06597)
- Gryzun, putative trafficking through Golgi (PF07919)
- Integrin alpha (PF08441)
- Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A (PF12222)
- Protein of unknown function (DUF3999) (PF13163)
- Oxygen tolerance (PF13584)
- Domain of unknown function (DUF4403) (PF14356)
- Type I membrane glycoproteins cell-cell fusogen (PF14884)
- Domain of unknown function (DUF4613) (PF15390)


PNSF no. 4


- Zinc-binding domain of primase-helicase (PF08273)
- NADH pyrophosphatase zinc ribbon domain (PF09297)
- Uncharacterised protein family UPF0547 (PF10571)
- Protein of unknown function (DUF3133) (PF11331)
- zinc-ribbon domain (PF13240)
- zinc-ribbon domain (PF13248)
- zinc-ribbon domain (PF13717)
- zinc-ribbon domain (PF13719)
- Nudix N-terminal (PF14803)


PNSF no. 5


- Viral enhancin protein (PF03272)
- RNA polymerase-associated transcription specificity factor, Rap94 (PF03294)
- Glycosyl hydrolase family 81 (PF03639)
- Poxvirus early transcription factor (VETF), large subunit (PF04441)
- Reovirus minor core protein Mu-2 (PF07781)
- Cell cycle and development regulator (PF10221)
- Mitochondrial protein from FMP27 (PF10344)
- Utp8 family (PF10395)


PNSF no. 6


- Type II secretion system (T2SS), protein N (PF01203)
- Uncharacterized protein conserved in bacteria (DUF2125) (PF09898)
- Protein of unknown function (DUF2993) (PF11209)
- Dicarboxylate transport (PF11739)
- AsmA-like C-terminal region (PF13109)
- Protein of unknown function (PF13116)
- AsmA-like C-terminal region (PF13502)


PNSF no. 7


- Phage portal protein (PF04860)
- Phage portal protein, SPP1 Gp6-like (PF05133)
- Phage portal protein, lambda family (PF05136)
- Protein of unknown function (DUF1073) (PF06381)
- Bacteriophage T4-like capsid assembly protein (Gp20) (PF07230)
- Bacteriophage head to tail connecting protein (PF12236)


PNSF no. 8


- Major fimbrial subunit protein (FimA) (PF06321)
- Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 (PF08842)
- Protein of unknown function (DUF3988) (PF13149)
- Domain of unknown function (DUF4493) (PF14900)
- Protein of unknown function (DUF4622) (PF15415)


PNSF no. 9


- TraK protein (PF06586)
- Protein of unknown function (DUF2381) (PF09544)
- Protein of unknown function (DUF3438) (PF11920)
- Protein of unknown function (DUF3625) (PF12293)
- Domain of unknown function (DUF4138) (PF13595)


PNSF no. 10


- Hydroxyneurosporene synthase (CrtC) (PF07143)
- Svf1-like (PF08622)
- Protein of unknown function (DUF2804) (PF10974)
- Tocopherol cyclase (PF14249)


PNSF no. 11


- 3A/RNA2 movement protein family (PF00803)
- Viral movement protein (MP) (PF01107)
- Bromovirus movement protein (PF01573)


PNSF no. 12


- HNH endonuclease (PF01844)
- HNH endonuclease (PF13391)
- HNH endonuclease (PF13395)


PNSF no. 13


- 56kDa selenium binding protein (SBP56) (PF05694)
- Protein of unknown function (DUF1513) (PF07433)
- Lactonase, 7-bladed beta-propeller (PF10282)


PNSF no. 14


- Plasmid recombination enzyme (PF01076)
- MobA/MobL family (PF03389)
- Relaxase/Mobilisation nuclease domain (PF03432)


PNSF no. 15


- Replication factor A protein 3 (PF08661)
- Telomere capping, CST complex subunit (PF12658)
- Telomere-capping, CST complex subunit (PF15490)


PNSF no. 16


- 'Cold-shock' DNA-binding domain (PF00313)
- Rho termination factor, RNA-binding domain (PF07497)
- Ribonuclease B OB domain (PF08206)


PNSF no. 17


- Metallothionein (PF01439)
- Metallothionein (PF05522)
- Eukaryotic metallothionein (PF12749)


PNSF no. 18


- Chitobiase/beta-hexosaminidase C-terminal domain (PF03174)
- Fn3 associated (PF13287)
- Chitobiase/beta-hexosaminidase C-terminal domain (PF13290)


PNSF no. 19


- Glycine zipper 2TM domain (PF05433)
- YMGG-like Gly-zipper (PF13441)
- Glycine zipper (PF13488)


PNSF no. 20


- Uncharacterised protein family (UPF0093) (PF03653)
- Invasion gene expression up-regulator, SirB (PF04247)
- Protein of unknown function (DUF1516) (PF07457)


PNSF no. 21


- YOP proteins translocation protein K (YscK) (PF06578)
- Bacterial type III secretion apparatus protein (OrgA_MxiK) (PF09482)
- Bacterial type III secretion protein (HrpB4) (PF09502)


PNSF no. 22


- Putative transposase, YhgA-like (PF04754)
- Protein of unknown function (DUF2887) (PF11103)
- PD-(D/E)XK nuclease family transposase (PF12784)


PNSF no. 23


- Fimbrial protein (PF00419)
- Spore Coat Protein U domain (PF05229)
- Domain of unknown function (DUF4402) (PF14352)


PNSF no. 24


- Transcription initiation factor IIF, beta subunit (PF02270)
- RNA polymerase III transcription factor (TF)IIIC subunit (PF09734)
- RNA polymerase II elongation factor ELL (PF10390)


PNSF no. 25


- Bacterial PH domain (PF03703)
- Bacterial PH domain (PF06713)
- Bacterial PH domain (PF10882)


PNSF no. 26


- PPIC-type PPIASE domain (PF00639)
- PPIC-type PPIASE domain (PF13145)
- PPIC-type PPIASE domain (PF13616)


PNSF no. 27


- Repair protein Rad1/Rec1/Rad17 (PF02144)
- Hus1-like protein (PF04005)
- Rad9 (PF04139)


PNSF no. 28


- Initiator Replication protein (PF01051)
- Replication protein C (RepC) (PF06504)
- Replication initiator protein A (PF10134)


PNSF no. 29


- 4Fe-4S binding domain (PF00037)
- 4Fe-4S binding domain (PF12797)
- 4Fe-4S binding domain (PF12837)


PNSF no. 30


- Phage late control gene D protein (GPD) (PF05954)
- Prophage endopeptidase tail (PF06605)
- Siphovirus ReqiPepy6 Gp37-like protein (PF14594)


PNSF no. 31


- Trypanosome variant surface glycoprotein (A-type) (PF00913)
- Invariant surface glycoprotein (PF11727)
- Trypanosomal VSG domain (PF13206)


PNSF no. 32


- Thioesterase-like superfamily (PF13622)
- Polyketide synthase dehydratase (PF14765)


PNSF no. 33


- TfoX C-terminal domain (PF04994)
- Pathogenicity locus (PF11731)


PNSF no. 34


- Rifin/stevor family (PF02009)
- Baculoviral E56 protein, specific to ODV envelope (PF04639)


PNSF no. 35


- Transcription factor S-II (TFIIS) (PF01096)
- Baculoviridae late expression factor 5 C-terminal domain (PF11792)


PNSF no. 36


- Bacterial Ig-like domain (group 3) (PF12245)
- Bacterial Ig-like domain (group 3) (PF13754)


PNSF no. 37


- E2 binding domain (PF08825)
- Ubiquitin/SUMO-activating enzyme ubiquitin-like domain (PF14732)


PNSF no. 38


- Protein of unknown function (DUF1129) (PF06570)
- Protein of unknown function (DUF1700) (PF08006)


PNSF no. 39


- Closterovirus coat protein (PF01785)
- Trichovirus coat protein (PF05892)


PNSF no. 40


- Protein of unknown function C-terminus (DUF2399) (PF09664)
- Uncharacterized protein conserved in bacteria C-term(DUF2220) (PF09983)


PNSF no. 41


- Erythropoietin receptor, ligand binding (PF09067)
- Interleukin-6 receptor alpha chain, binding (PF09240)


PNSF no. 42


- FAM183A and FAM183B related (PF14886)
- Normal lung function maintenance, Low in Lung Cancer 1 protein (PF14945)


PNSF no. 43


- tRNA Pseudouridine synthase II, C terminal (PF09142)
- Pseudouridine synthase II TruB, C-terminal (PF09157)


PNSF no. 44


- HrpE/YscL/FliH and V-type ATPase subunit E (PF06188)
- Nodulation protein NolV (PF06635)


PNSF no. 45


- Adenovirus E3 region protein CR2 (PF02439)
- Transmembrane alpha-helix domain (PF08693)


PNSF no. 46


- 37-kD nucleoid-associated bacterial protein (PF04245)
- Domain of unknown function (DUF4317) (PF14199)


PNSF no. 47


- Antimicrobial peptide tachystatin A (PF11406)
- Antimicrobial chitin binding protein tachystatin B (PF11478)


PNSF no. 48


- PPR repeat (PF01535)
- Pentatricopeptide repeat domain (PF13812)


PNSF no. 49


- RloB-like protein (PF13707)
- Domain of unknown function (DUF4276) (PF14103)


PNSF no. 50


- Consortin C-terminus (PF15281)
- Domain of unknown function (DUF4658) (PF15555)


PNSF no. 51


- Lipopolysaccharide-assembly, LptC-related (PF06835)
- OstA-like protein (PF13100)


PNSF no. 52


- Domain of unknown function (DUF1839) (PF08893)
- NlpC/p60-like transpeptidase (PF14399)


PNSF no. 53


- Protein of unknown function (DUF2806) (PF10987)
- Domain of unknown function (DUF4393) (PF14337)


PNSF no. 54


- Integral peroxisomal membrane peroxin (PF06398)
- Lipase maturation factor (PF06762)


PNSF no. 55


- Protein of unknown function (DUF3823) (PF12866)
- Domain of unknown function (DUF4249) (PF14054)


PNSF no. 56


- KH domain (PF07650)
- KH domain (PF13083)


PNSF no. 57


- Transport protein Avl9 (PF09794)
- Uncharacterized conserved protein (DUF2347) (PF09804)


PNSF no. 58


- F-box associated (PF07734)
- F-box associated domain (PF08268)


PNSF no. 59


- Intracellular septation protein A (PF04279)
- Protein of unknown function (DUF3159) (PF11361)


PNSF no. 60


- Susd and RagB outer membrane lipoprotein (PF12741)
- Starch-binding associating with outer membrane (PF12771)


PNSF no. 61


- TIM21 (PF08294)
- Cytochrome oxidase complex assembly protein 1 (PF08695)


PNSF no. 62


- Fusion glycoprotein F0 (PF00523)
- Gypsy protein (PF07253)


PNSF no. 63


- bZIP transcription factor (PF00170)
- Basic region leucine zipper (PF07716)


PNSF no. 64


- Conotoxin O-superfamily (PF08087)
- PhTx neurotoxin family (PF08116)


PNSF no. 65


- Tripartite tricarboxylate transporter TctB family (PF07331)
- Protein of unknown function (DUF3180) (PF11377)


PNSF no. 66


- Golgin subfamily A member 7/ERF4 family (PF10256)
- Domain of unknown function (DUF4646) (PF15496)


PNSF no. 67


- Calcium binding and coiled-coil domain (CALCOCO1) like (PF07888)
- Testis-specific serine kinase substrate (PF15358)


PNSF no. 68


- UL73 viral envelope glycoprotein (PF03554)
- Herpesvirus UL49.5 envelope/tegument protein (PF05702)


PNSF no. 69


- Marek's disease glycoprotein A (PF02124)
- Equine herpesvirus glycoprotein gp2 (PF05955)


PNSF no. 70


- Sodium / potassium ATPase beta chain (PF00287)
- Protein of unknown function (DUF3430) (PF11912)


PNSF no. 71


- Dynein heavy chain, N-terminal region 2 (PF08393)
- Protein of unknown function (DUF3542) (PF12061)


PNSF no. 72


- Gene 25-like lysozyme (PF04965)
- Protein of unknown function (DUF2634) (PF10934)


PNSF no. 73


- Cornifin (SPRR) family (PF02389)
- Formin Homology Region 1 (PF06346)


PNSF no. 74


- Condensation domain (PF00668)
- Wax ester synthase-like Acyl-CoA acyltransferase domain (PF03007)


PNSF no. 75


- SGF29 tudor-like domain (PF07039)
- Domain of unknown function (DUF4537) (PF15057)


PNSF no. 76


- Ferredoxin-dependent bilin reductase (PF05996)
- Red chlorophyll catabolite reductase (RCC reductase) (PF06405)


PNSF no. 77


- Transposase, Mutator family (PF00872)
- Uncharacterised protein family (UPF0236) (PF06782)


PNSF no. 78


- gag-polypeptide of LTR copia-type (PF14223)
- gag-polypeptide of LTR copia-type (PF14227)


PNSF no. 79


- Replication factor-A protein 1, N-terminal domain (PF04057)
- BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 (PF09103)


PNSF no. 80


- Protein of unknown function (DUF2397) (PF09660)
- Protein of unknown function (DUF3375) (PF11855)


PNSF no. 81


- Mnd1 family (PF03962)
- Tat binding protein 1(TBP-1)-interacting protein (TBPIP) (PF07106)


PNSF no. 82


- HWE histidine kinase (PF07536)
- Histidine kinase (PF07568)


PNSF no. 83


- SMI1 / KNR4 family (SUKH-1) (PF09346)
- SMI1-KNR4 cell-wall (PF14568)


PNSF no. 84


- Uncharacterised protein family (UPF0150) (PF03681)
- Domain of unknown function (DUF1902) (PF08972)


PNSF no. 85


- Protein of unknown function (DUF4245) (PF14030)
- Domain of unknown function (DUF4367) (PF14285)


PNSF no. 86


- SICA extracellular beta domain (PF12878)
- SICA extracellular alpha domain (PF12887)


PNSF no. 87


- VirB8 protein (PF04335)
- Protein of unknown function (DUF2895) (PF11444)


PNSF no. 88


- Phage Terminase (PF03354)
- Phage terminase large subunit (GpA) (PF05876)


PNSF no. 89


- Family of unknown function (DUF694) (PF05107)
- CT1975-like protein (PF09344)


PNSF no. 90


- Transferase family (PF02458)
- Alcohol acetyltransferase (PF07247)


PNSF no. 91


- ICP0-binding domain of Ubiquitin-specific protease 7 (PF12436)
- Ubiquitin-specific protease C-terminal (PF14533)


PNSF no. 92


- Male specific sperm protein (PF03940)
- Keratin, high sulfur B2 protein (PF13885)


PNSF no. 93


- 4Fe-4S double cluster binding domain (PF13484)
- 4Fe-4S dicluster domain (PF13746)


PNSF no. 94


- gag gene protein p24 (core nucleocapsid protein) (PF00607)
- Gag P30 core shell protein (PF02093)


PNSF no. 95


- Peptidase C80 family (PF11713)
- Domain of unknown function (DUF4347) (PF14252)


PNSF no. 96


- Corticotropin-releasing factor family (PF00473)
- Agonist of corticotropin releasing factor R2, Urocortin-2 (PF11613)


PNSF no. 97


- Beta-galactosidase C-terminal domain (PF08533)
- Cyclo-malto-dextrinase C-terminal domain (PF10438)


PNSF no. 98


- Glycosyl hydrolase family 65, N-terminal domain (PF03636)
- Glycosyl hydrolase family 65, N-terminal domain (PF14498)


PNSF no. 99


- Coatomer WD associated region (PF04053)
- Vps16, N-terminal region (PF04841)


PNSF no. 100


- TadE-like protein (PF07811)
- Putative Flp pilus-assembly TadE/G-like (PF13400)


PNSF no. 101


- Phage tail sheath protein (PF04984)
- Protein of unknown function (DUF3383) (PF11863)


PNSF no. 102


- Glutathione S-transferase, C-terminal domain (PF00043)
- Glutathione S-transferase, C-terminal domain (PF14497)


PNSF no. 103


- Isoprenylcysteine carboxyl methyltransferase (ICMT) family (PF04140)
- Phospholipid methyltransferase (PF04191)


PNSF no. 104


- Ciliary neurotrophic factor (PF01110)
- Plethodontid receptivity factor PRF (PF06875)


PNSF no. 105


- Serum albumin family (PF00273)
- Domain of unknown function (DUF19) (PF01579)


PNSF no. 106


- Inhibitor of sigma-G Gin (PF10764)
- Domain of unknown function (DUF4428) (PF14471)


PNSF no. 107


- Phage tail fibre adhesin Gp38 (PF05268)
- Glycine rich protein (PF12810)


PNSF no. 108


- Surface antigen variable number repeat (PF07244)
- POTRA domain, ShlB-type (PF08479)


PNSF no. 109


- Complex 1 protein (LYR family) (PF05347)
- Complex1_LYR-like (PF13232)


PNSF no. 110


- Mu DNA-binding domain (PF02316)
- Putative transcription regulator (DUF1323) (PF07037)


PNSF no. 111


- Domain of unknown function (DUF4352) (PF11611)
- Domain of unknown function (DUF4354) (PF14263)


PNSF no. 112


- CD20-like family (PF04103)
- L6 membrane protein (PF05805)


PNSF no. 113


- Acetoacetate decarboxylase (ADC) (PF06314)
- Uncharacterized conserved protein (COG2071) (PF09844)


PNSF no. 114


- LBP / BPI / CETP family, N-terminal domain (PF01273)
- Haemolymph juvenile hormone binding protein (JHBP) (PF06585)


PNSF no. 115


- Asp/Glu/Hydantoin racemase (PF01177)
- AroM protein (PF07302)


PNSF no. 116


- Phage integrase, N-terminal SAM-like domain (PF02899)
- Phage integrase, N-terminal SAM-like domain (PF13495)


PNSF no. 117


- Flp/Fap pilin component (PF04964)
- Protein of unknown function (DUF4244) (PF14029)


PNSF no. 118


- Protein of unknown function (DUF3616) (PF12275)
- Esterase-like activity of phytase (PF13449)


PNSF no. 119


- Type II secretion system (T2SS), protein M (PF04612)
- GspL periplasmic domain (PF12693)


PNSF no. 120


- Adenovirus 15.3kD protein in E3 region (PF03307)
- Adenovirus E3A (PF05248)


PNSF no. 121


- Autophagy protein Apg6 (PF04111)
- UV radiation resistance protein and autophagy-related subunit 14 (PF10186)


PNSF no. 122


- T5orf172 domain (PF10544)
- Meiotically up-regulated gene 113 (PF13455)


PNSF no. 123


- Carlavirus endopeptidase (PF05379)
- Putative closterovirus papain-like endopeptidase (PF05413)


PNSF no. 124


- Perilipin family (PF03036)
- Transcription factor Opi1 (PF08618)


PNSF no. 125


- Recombination protein O N terminal (PF11967)
- RecO N terminal (PF13114)


PNSF no. 126


- C-terminal domain of CHU protein family (PF13585)
- FlgD Ig-like domain (PF13860)